PCR Detection of Type I Polyketide Synthase Genes in Myxobacteria | Zendy

Hisayuki Komaki | Zendy; Ryosuke Fudou | Zendy; Takashi Iizuka | Zendy; Daisuke Nakajima | Zendy; Koei Okazaki | Zendy; Daisuke Shibata | Zendy; Makoto Ojika | Zendy; Shigeaki Harayama | Zendy

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PCR Detection of Type I Polyketide Synthase Genes in Myxobacteria

Author(s) -

Hisayuki Komaki,

Ryosuke Fudou,

Takashi Iizuka,

Daisuke Nakajima,

Koei Okazaki,

Daisuke Shibata,

Makoto Ojika,

Shigeaki Harayama

Publication year - 2008

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.00224-08

Subject(s) - myxobacteria , polyketide synthase , biology , gene , polyketide , genetics , computational biology , bacteria , biosynthesis

The diversity of type I modular polyketide synthase (PKS) was explored by PCR amplification of DNA encoding ketosynthase and acyltransferase domains in myxobacteria. The sequencing of the amplicons revealed that many PKS genes were distantly related to the published sequences. Thus, myxobacteria may be excellent resources for novel and diverse polyketides.

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