Temperature-Dependent Parasitic Relationship between Legionella pneumophila and a Free-Living Amoeba ( Acanthamoeba castellanii )
Author(s) -
Akira Ohno,
Naoyuki Kato,
Ryota Sakamoto,
Soichiro Kimura,
Keizo Yamaguchi
Publication year - 2008
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.00083-08
Subject(s) - legionella pneumophila , amoeba (genus) , acanthamoeba , microbiology and biotechnology , biology , legionella , bacteria , protozoa , microorganism , genetics
We analyzed the effects of temperature on the interaction of Legionella pneumophila with Acanthamoeba castellanii. At <20 degrees C, overexpression of type 1 metacaspase, a stimulator of A. castellanii encystation, was associated with a reduced number of bacteria within amoeba. At low temperatures, A. castellanii seems to eliminate L. pneumophila by encystation and digestion.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom