Open AccessEnzymatic Modification of Aminoglycoside Antibiotics: a New 3- N -Acetylating Enzyme from a Pseudomonas aeruginosa Isolate
Author(s) -
S. Biddlecome,
Michael J. Haas,
Julian Davies,
George H. Miller,
D. F. Rane,
Peter J. L. Daniels
Publication year - 1976
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.9.6.951
Subject(s) - aminoglycoside , pseudomonas aeruginosa , enzyme , antibiotics , microbiology and biotechnology , chemistry , pseudomonas , biology , biochemistry , bacteria , genetics
A new 3-N -aminoglycoside acetyltransferase is described, which possesses a wider substrate range than any such enzyme so far discovered in clinical isolates of antibiotic-resistant bacteria.