Open AccessComparison of In Vitro Antimicrobial Activity of Cefamandole and Cefazolin with Cephalothin Against over 8,000 Clinical Bacterial Isolates
Author(s) -
Ronald N. Jones,
Peter Fuchs
Publication year - 1976
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.9.6.1066
Subject(s) - cefazolin , cefamandole , broth microdilution , antimicrobial , microbiology and biotechnology , cefalotin , cephalosporin , biology , chemistry , minimum inhibitory concentration , antibiotics
Antimicrobial susceptibility to cefamandole versus cephalothin and cefazolin versus cephalothin was compared by the broth microdilution method against 3,000 and 5,895 clinical bacterial isolates, respectively. Cefamandole and, to a lesser degree, cefazolin showed greater activity than cephalothin againstEnterobacteriaceae , but the three drugs were comparable against gram-positive cocci.