Biogenetic Origin of the d -Isoleucine and N -Methyl- l -Alloisoleucine Residues in the Actinomycins | Zendy

Takehiko Yajima | Zendy; Kaarin T. Mason | Zendy; Edward Katz | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Biogenetic Origin of the d -Isoleucine and N -Methyl- l -Alloisoleucine Residues in the Actinomycins

Author(s) -

Takehiko Yajima,

Kaarin T. Mason,

Edward Katz

Publication year - 1976

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.9.2.224

Subject(s) - isoleucine , chemistry , biosynthesis , stereochemistry , biochemistry , amino acid , leucine , gene

Studies with14 C-labeled isoleucine stereisomers have established thatl -alloisoleucine,d -alloisoleucine, andd -isoleucine may function as precursors for the biogenesis ofd -isoleucine andN -methyl-l -alloisoleucine residues in actinomycin.l -[14 C]isoleucine appears to be employed chiefly ford -alloisoleucine (andN -methylisoleucine [?] formation); however, its role in the biosynthesis ofd -isoleucine andN -methylalloisoleucine remains unclear. The potential pathway of biosynthesis ofd -isoleucine andN -methyl-l -isoleucine is discussed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research