Open AccessInduction of Erythromycin Resistance in Staphylococcus aureus by Erythromycin Derivatives
Author(s) -
Sidney Pestka,
Robert Vince,
Ronald A. LeMahieu,
Florence Weiss,
Lucille Fern,
Joel Unowsky
Publication year - 1976
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.9.1.128
Subject(s) - erythromycin , staphylococcus aureus , microbiology and biotechnology , antibacterial activity , antibacterial agent , chemistry , antibiotics , biology , bacteria , genetics
The ability of 53 erythromycin analogues to induce resistance to erythromycin inStaphlococcus aureus was evaluated. Only derivatives with antibacterial activity induced resistance, although some antibacterial compounds did not induce resistance. No derivatives without antibacterial activity but with ability to induce resistance were found.