Stability of Frozen Rat Plasma Containing Different Antibiotics | Zendy

MARIA ANTONIETTA BERTI | Zendy; M Maccari | Zendy

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Stability of Frozen Rat Plasma Containing Different Antibiotics

Author(s) -

MARIA ANTONIETTA BERTI,

M Maccari

Publication year - 1975

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.8.6.633

Subject(s) - cephaloridine , oxytetracycline , antibiotics , ampicillin , penicillin , tetracycline , erythromycin , streptomycin , microbiology and biotechnology , cephalosporin , chemistry , biology

The antibiotic activity was determined at different intervals of time on plasma samples, taken from rats treated with a certain number of commonly used antibiotics, and kept at −20 C up to 8 weeks. The results of the microbiological assays demonstrate that the stability of the antibiotics in the frozen plasma decreases in the following order: oxytetracycline > cephalexin, streptomycin, erythromycin > demeclocycline > ampicillin, amoxycillin > penicillin G, cephaloridine, rolitetracycline, and tetracycline.

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