Open AccessStability of Frozen Rat Plasma Containing Different Antibiotics
Author(s) -
Maria Antonietta Berti,
M Maccari
Publication year - 1975
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.8.6.633
Subject(s) - cephaloridine , oxytetracycline , antibiotics , ampicillin , penicillin , tetracycline , erythromycin , streptomycin , microbiology and biotechnology , cephalosporin , chemistry , biology
The antibiotic activity was determined at different intervals of time on plasma samples, taken from rats treated with a certain number of commonly used antibiotics, and kept at −20 C up to 8 weeks. The results of the microbiological assays demonstrate that the stability of the antibiotics in the frozen plasma decreases in the following order: oxytetracycline > cephalexin, streptomycin, erythromycin > demeclocycline > ampicillin, amoxycillin > penicillin G, cephaloridine, rolitetracycline, and tetracycline.