Open AccessIn Vitro Susceptibility of Selected Bacteria to Three Diphosphonia Heterocyclic Compounds
Author(s) -
Frederick C. Pearson,
Theodore Lemeshka,
Frank Ferrara,
John C. Williams
Publication year - 1975
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.8.5.608
Subject(s) - antibacterial activity , bacteria , in vitro , gram , gram negative bacteria , gram positive bacteria , antibacterial agent , chemistry , microbiology and biotechnology , biology , biochemistry , escherichia coli , genetics , gene
The antibacterial activity of 1,1,4,4-tetraphenyl-1,4-diphosphonia-2,5-diphenylcyclohexadi-2,5-ene dichloride and two of its derivatives were screened for activity using the disk method. All derivatives exhibited antibacterial activity against gram-positive organisms tested, but little inhibition of gram-negative species was noted.