Plasmid-Determined Resistance to Erythromycin: Comparison of Strains of Streptococcus faecalis and Streptococcus pyogenes with Regard to Plasmid Homology and Resistance Inducibility | Zendy

Yoshihiko Yagi | Zendy; Arthur E. Franke | Zendy; Don B. Clewell | Zendy

Open Access

Plasmid-Determined Resistance to Erythromycin: Comparison of Strains of Streptococcus faecalis and Streptococcus pyogenes with Regard to Plasmid Homology and Resistance Inducibility

Author(s) -

Yoshihiko Yagi,

Arthur E. Franke,

Don B. Clewell

Publication year - 1975

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.7.6.871

Subject(s) - plasmid , streptococcus pyogenes , microbiology and biotechnology , lincomycin , streptococcus , erythromycin , streptococcaceae , enterococcus faecalis , biology , dna , antibiotics , bacteria , staphylococcus aureus , genetics

Streptococcus faecalis strains DS-5 and Streptococcus pyogenes strain AC-1 both have a 17 million dalton plasmid that determines resistance to erythromycin, lincomycin, and vernamycin B(alpha). The results of deoxyribonucleic acid-deoxyribonucleic acid hybridization experiments indicate that the two plasmids are about 95% homologous. It was also shown that erythromycin resistance is inducible in AC-1 and constitutive in DS-5.

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