Evaluation of the Modified Broth-Disk Method for Determining Antibiotic Susceptibilities of Anaerobic Bacteria | Zendy

Donna J. Blazevic | Zendy

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Evaluation of the Modified Broth-Disk Method for Determining Antibiotic Susceptibilities of Anaerobic Bacteria

Author(s) -

Donna J. Blazevic

Publication year - 1975

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.7.6.721

Subject(s) - clindamycin , microbiology and biotechnology , penicillin , ampicillin , anaerobic bacteria , chloramphenicol , tetracycline , anaerobic exercise , agar dilution , antibiotics , erythromycin , bacteria , agar , biology , chemistry , minimum inhibitory concentration , physiology , genetics

A total of 110 strains of anaerobic bacteria including 9 different genera was tested for antibiotic susceptibility by the modified broth-disk method of Wilkins and Thiel (1973), using prereduced media and the VPI anaerobic culture system. Results were compared with those obtained with an agar dilution technique with incubation in a GasPak jar. There was greater than 95% agreement between the two methods with ampicillin, cephalothin, chloramphenicol, and clindamycin, and 90% or greater agreement with erythromycin, penicillin, and tetracycline.

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