Open AccessIn Vitro Activity of Penicillins Against Anaerobes
Author(s) -
Francis P. Tally,
Nilda V. Jacobus,
John G. Bartlett,
Sherwood L. Gorbach
Publication year - 1975
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.7.4.413
Subject(s) - carbenicillin , bacteroides fragilis , microbiology and biotechnology , penicillin , in vitro , bacteroides , biology , anaerobic bacteria , antibiotics , ampicillin , chemistry , bacteria , biochemistry , genetics
The in vitro susceptibility of 162 anaerobic isolates from clinical material were tested to pencillin G, BL-P1654, and carbenicillin. Penicillin G and BL-P1654 showed good activity againstBacteroides fragilis , but only 60% of strains were susceptible to carbenicillin at achievable blood levels (128 μg/ml).