Open AccessImproved Acetylating Radioenzymatic Assay of Amikacin, Tobramycin, and Sisomicin in Serum
Author(s) -
Paul Stevens,
Lowell S. Young,
William L. Hewitt
Publication year - 1975
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.7.3.374
Subject(s) - sisomicin , tobramycin , amikacin , microbiology and biotechnology , medicine , gentamicin , chemistry , pharmacology , antibiotics , biology
The acetylating radioenzymatic assay of aminoglycosides was modified by using [(3)H]acetyl coenzyme A as cosubstrate. This modification reduces the cost of the method by at least one-half without sacrificing rapidity or accuracy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom