Open AccessMicrobiological Assays and Bioautography of Maytansine and Its Homologues
Author(s) -
L. J. Haňka,
Michael Barnett
Publication year - 1974
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.6.5.651
Subject(s) - microbiology and biotechnology , chemistry , bioassay , chromatography , biology , pharmacology , genetics
A quantitative microbiological assay and a bioautography system withPenicillium avellaneum UC-4376 was developed for the antitumor drugs maytansine, and its homologues, maytanprine and maytanbutine. The susceptibility of the assay is 1.5 μg/ml.
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