Open AccessComparison of In Vitro Antibacterial Activities of Gentamicin and Verdamicin
Author(s) -
Pauline K. W. Yu,
John A. Washington
Publication year - 1974
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.6.4.526
Subject(s) - gentamicin , providencia , aminoglycoside , pseudomonas aeruginosa , proteus , microbiology and biotechnology , in vitro , enterobacteriaceae , antibiotics , biology , proteus mirabilis , bacteria , escherichia coli , biochemistry , genetics , gene
The in vitro activities of verdamicin and gentamicin were studied in parallel against 1,049 bacterial isolates. Verdamicin demonstrated activity similar to that of gentamicin against members of the familyEnterobacteriaceae and againstPseudomonas aeruginosa at 2 and 8 μg/ml, respectively.Proteus rettgeri andProvidencia stuartii were notably more susceptible to verdamicin. The new aminoglycoside was also highly active against staphylococci but was not effective against group D streptococci.