Open AccessIsolation and Characterization of a Kanamycin Resistance Plasmid from Staphylococcus aureus
Author(s) -
Paul W. Stiffler,
Helen M. Sweeney,
Marc Schneider,
Sidney Cohen
Publication year - 1974
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.6.4.516
Subject(s) - kanamycin , plasmid , neomycin , staphylococcus aureus , microbiology and biotechnology , antibiotics , biology , gene , bacteria , genetics
A circular covalently closed duplex deoxyribonucleic acid plasmid carrying genes for resistance to kanamycin/neomycin has been identified in Staphylococcus aureus E419. The plasmid has a molecular size of 9.2 x 10(6) daltons and can be transduced into or can transform competent susceptible strains of S. aureus to kanamycin/neomycin resistance.
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