Open AccessIn Vitro Uptake of Isometamidium and Diminazene by Trypanosoma brucei
Author(s) -
Pamela Girgis-Takla,
Dinah M. James
Publication year - 1974
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.6.3.372
Subject(s) - diminazene , trypanosoma brucei , in vitro , trypanosoma evansi , biology , trypanocidal agent , trypanosoma , pharmacology , trypanosomiasis , virology , biochemistry , gene
The cattle trypanocide, isometamidium, was readily taken up by inactivated Trypanosoma brucei, while its uptake by living parasites was reduced or inhibited by plasma. In both respects isometamidium differs from diminazene.
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