Tissue Penetration of Telavancin after Intravenous Administration in Healthy Subjects | Zendy

Heather K. Sun | Zendy; Kenneth L. Duchin | Zendy; Charles H. Nightingale | Zendy; JengPyng Shaw | Zendy; Julie D. Seroogy | Zendy; David P. Nicolau | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Tissue Penetration of Telavancin after Intravenous Administration in Healthy Subjects

Author(s) -

Heather K. Sun,

Kenneth L. Duchin,

Charles H. Nightingale,

JengPyng Shaw,

Julie D. Seroogy,

David P. Nicolau

Publication year - 2006

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.50.2.788-790.2006

Subject(s) - pharmacokinetics , penetration (warfare) , medicine , body fluid , pharmacology , plasma concentration , interstitial fluid , operations research , engineering

The pharmacokinetic disposition of telavancin administered 7.5 mg/kg of body weight every 24 h was determined in plasma and skin blister fluid. The mean penetration of telavancin into blister fluid was 40%. This study reveals that adequate concentrations are achieved in both plasma and blister fluid for pathogens frequently implicated in skin and soft tissue infections.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research