Open AccessEmergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum β-Lactamase in Austria
Author(s) -
Alexandra Eisner,
Elizabeth J. Fagan,
Gebhard Feierl,
Harald H. Kessler,
Egon Marth,
David M. Livermore,
Neil Woodford
Publication year - 2006
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.50.2.785-787.2006
Subject(s) - enterobacteriaceae , microbiology and biotechnology , escherichia coli , biology , pulsed field gel electrophoresis , beta lactamase , klebsiella pneumoniae , klebsiella , molecular epidemiology , strain (injury) , veterinary medicine , genotype , medicine , genetics , gene , anatomy
Among 149 extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.