Open AccessSusceptibility of Anaerobic Bacteria to Carbenicillin
Author(s) -
Donna J. Blazevic,
John M. Matsen
Publication year - 1974
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.5.5.462
Subject(s) - carbenicillin , bacteroides fragilis , microbiology and biotechnology , agar dilution , anaerobic bacteria , agar dilution method , eubacterium , minimum inhibitory concentration , bacteria , biology , bacteroides , agar , dilution , anaerobic exercise , chemistry , antibiotics , ampicillin , genetics , thermodynamics , physiology , physics
One hundred and seventy-one strains of anaerobes were tested for susceptibility to carbenicillin by using agar dilution, broth dilution, and two disk diffusion methods. The minimal inhibitory concentration (MIC) for 67% of 51 strains of Bacteroides fragilis, 7 of 9 strains of Bacteroides melaninogenicus, and all of 8 strains of Eubacterium was 100 mug or less per ml. The MICs of the remaining anaerobes were 50 mug or less per ml. The broth dilution results were felt to be the most accurate of the four methods utilized.
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