Open AccessDecreasing Prevalence of β-Lactamase Production among Respiratory Tract Isolates of Haemophilus influenzae in the United States
Author(s) -
Kristopher P. Heilmann,
C. Rice,
Ashley L. Miller,
Norman N. Miller,
Susan E. Beekmann,
Michael A. Pfaller,
Sandra Richter,
Gary V. Doern
Publication year - 2005
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.49.6.2561-2564.2005
Subject(s) - haemophilus influenzae , microbiology and biotechnology , sulfamethoxazole , trimethoprim , respiratory tract , antimicrobial , respiratory tract infections , haemophilus , pasteurellaceae , pathogen , biology , medicine , antibiotics , bacteria , respiratory system , genetics
A total of 986 isolates of Haemophilus influenzae from patients with respiratory tract infections in 45 United States medical centers were characterized during the winter of 2002-2003. beta-Lactamase production was noted with 26.2% of isolates; 14.6% were resistant to trimethoprim-sulfamethoxazole. Resistance to other relevant antimicrobial agents was extremely uncommon. In comparison to the results of four previous national surveys conducted since 1994, the prevalence of beta-lactamase production with this pathogen appears to be decreasing.