Open AccessActivities of Telithromycin against 13,874 Streptococcus pneumoniae Isolates Collected between 1999 and 2003
Author(s) -
David J. Farrell,
D. Felmingham
Publication year - 2004
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.48.5.1882-1884.2004
Subject(s) - telithromycin , streptococcus pneumoniae , microbiology and biotechnology , ketolide , streptococcaceae , pneumococcal infections , streptococcus , biology , antibacterial agent , antibiotics , bacteria , genetics
Telithromycin MICs for 13,874 Streptococcus pneumoniae isolates collected in the first 3 years of the global PROTEKT study (1999 to 2003) were studied. There was no change in the distribution of telithromycin MICs over this period, even in countries where telithromycin is in use. The telithromycin MICs for 10 isolates (0.07%) were >/=4 micro g/ml, and these 10 isolates contained erm(B); there was no evidence of reproducible clonal spread between centers.