Open AccessIn Vitro Activities of DA-7867, a Novel Oxazolidinone, against Recent Clinical Isolates of Aerobic and Anaerobic Bacteria
Author(s) -
Dongeun Yong,
Jong Hwa Yum,
Kyungwon Lee,
Yunsop Chong,
Sun Jin Choi,
Jinsu Rhee
Publication year - 2004
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.48.1.352-357.2004
Subject(s) - linezolid , microbiology and biotechnology , antimicrobial , anaerobic bacteria , bacteria , aerobic bacteria , in vitro , anaerobic exercise , gram positive bacteria , biology , chemistry , pharmacology , biochemistry , staphylococcus aureus , physiology , vancomycin , genetics
In vitro activities of DA-7867, a novel oxazolidinone, were compared to those of linezolid and commonly used antimicrobials. DA-7867 had the lowest MIC for 90% of the aerobic gram-positive bacterial strains tested, </=0.25 micro g/ml, and it was more potent than linezolid.