Lack of In Vitro Antimicrosporidian Activity of Thalidomide | Zendy

Olivier Ridoux | Zendy; Michel Drancourt | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Lack of In Vitro Antimicrosporidian Activity of Thalidomide

Author(s) -

Olivier Ridoux,

Michel Drancourt

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.9.2305

Subject(s) - thalidomide , in vitro , enteritis , pharmacology , cytotoxic t cell , chemistry , biology , microbiology and biotechnology , immunology , biochemistry , multiple myeloma

Thalidomide was evaluated for its in vitro activity against Encephalitozoon species by using the MRC-5 cell system. A cytotoxic effect was observed for concentrations of 10(1) microg/ml (P < 10(5)) and 5 microg/ml (P < 10(5)). Thalidomide did not significantly inhibit the growth of any of the microsporidia under study. These data suggest that thalidomide is not an etiologic treatment in microsporidial enteritis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research