TEM-24 Produced by Four Different Species of Enterobacteriaceae , Including Providencia rettgeri , in a Single Patient | Zendy

Hélène Marchandin | Zendy; Christian Carrière | Zendy; Danielle Sirot | Zendy; Hélène Pierre | Zendy; H. Darbas | Zendy

Open Access

TEM-24 Produced by Four Different Species of Enterobacteriaceae , Including Providencia rettgeri , in a Single Patient

Author(s) -

Hélène Marchandin,

Christian Carrière,

Danielle Sirot,

Hélène Pierre,

H. Darbas

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.8.2069

Subject(s) - enterobacteriaceae , microbiology and biotechnology , providencia , plasmid , bacteria , biology , enterobacteriaceae infections , strain (injury) , escherichia coli , genetics , gene , anatomy

Four species of members of the familyEnterobacteriaceae harboring extended-spectrum β-lactamase (ESBL) were recovered in a single patient hospitalized in an intensive care unit. Among these isolates, we describe for the first time an ESBL-producingProvidencia rettgeri strain. Bacteria from the same species were shown to be genetically related by pulsed-field gel electrophoresis analysis. These strains produced the same TEM derivative ESBL, characterized as TEM-24. This enzyme had the peculiarity of being encoded by a large conjugative plasmid of 180 kb, never previously described for such an ESBL.

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