In Vitro Susceptibilities of Chlamydia pneumoniae Isolates from German Patients and Synergistic Activity of Antibiotic Combinations | Zendy

Heike Freidank | Zendy; Philipp Losch | Zendy; H. Vögele | Zendy; Margit WiedmannAlAhmad | Zendy

Open Access

In Vitro Susceptibilities of Chlamydia pneumoniae Isolates from German Patients and Synergistic Activity of Antibiotic Combinations

Author(s) -

Heike Freidank,

Philipp Losch,

H. Vögele,

Margit WiedmannAlAhmad

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.7.1808

Subject(s) - ofloxacin , roxithromycin , doxycycline , azithromycin , chlamydia , clarithromycin , antibiotics , microbiology and biotechnology , erythromycin , antibacterial agent , ciprofloxacin , biology , medicine , immunology

The susceptibilities of six Chlamydia pneumoniae type strains and of six German patient isolates to erythromycin, azithromycin, roxithromycin, clarithromycin, doxycycline, ofloxacin, and rifampin were investigated. MICs and minimal chlamydicidal concentrations were all within the ranges reported previously. Combinations of azithromycin with either ofloxacin, doxycycline, or rifampin, as well as combinations of three antibiotics (rifampin, azithromycin, and ofloxacin or doxycycline), showed synergistic activity against C. pneumoniae.

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