Effect of Azithromycin plus Rifampin versus That of Azithromycin Alone on the Eradication of Chlamydia pneumoniae from Lung Tissue in Experimental Pneumonitis | Zendy

Katerina Wolf | Zendy; Raffaele Malinverni | Zendy

Open Access

Effect of Azithromycin plus Rifampin versus That of Azithromycin Alone on the Eradication of Chlamydia pneumoniae from Lung Tissue in Experimental Pneumonitis

Author(s) -

Katerina Wolf,

Raffaele Malinverni

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.6.1491

Subject(s) - azithromycin , doxycycline , chlamydia , pneumonitis , microbiology and biotechnology , antibacterial agent , chlamydophila pneumoniae , antibiotics , chlamydiaceae , medicine , lung , pneumonia , biology , immunology

Azithromycin, doxycycline, and rifampin, alone or in combination, were tested in vitro against Chlamydia pneumoniae AR-39. The combination of azithromycin plus rifampin showed the strongest activity and produced higher rates of eradication of C. pneumoniae from lung tissues than azithromycin alone in experimental mouse pneumonitis.

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