Linezolid Activity Compared to Those of Selected Macrolides and Other Agents against Aerobic and Anaerobic Pathogens Isolated from Soft Tissue Bite Infections in Humans | Zendy

Ellie J. C. Goldstein | Zendy; Diane M. Citron | Zendy; C. Vreni Merriam | Zendy

Open Access

Linezolid Activity Compared to Those of Selected Macrolides and Other Agents against Aerobic and Anaerobic Pathogens Isolated from Soft Tissue Bite Infections in Humans

Author(s) -

Ellie J. C. Goldstein,

Diane M. Citron,

C. Vreni Merriam

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.6.1469

Subject(s) - pasteurella multocida , microbiology and biotechnology , pasteurella , linezolid , fusobacteria , eikenella corrodens , biology , moraxella catarrhalis , fusobacterium , agar dilution , bacteroides , haemophilus influenzae , antimicrobial , antibiotics , minimum inhibitory concentration , bacteria , staphylococcus aureus , vancomycin , bacteroidetes , 16s ribosomal rna , genetics

Linezolid was tested against 420 aerobes and anaerobes, including 148 Pasteurella isolates, by an agar dilution method. Linezolid was active against all Pasteurella multocida subsp. multocida and P. multocida subsp. septica isolates and most Pasteurella canis, Pasteurella dagmatis, and Pasteurella stomatis isolates. The MIC was </=2 microg/ml for staphylococci, streptococci, EF-4b, Weeksella zoohelcum, Fusobacterium nucleatum, other fusobacteria, Porphyromonas spp., Prevotella spp., peptostreptococci, and almost all Bacteroides tectum isolates.

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