Emergence of Fluoroquinolone Resistance among Multiply Resistant Strains of Streptococcus pneumoniae in Hong Kong | Zendy

PakLeung Ho | Zendy; TakLun Que | Zendy; Dominic NgaiChong Tsang | Zendy; TakKeung Ng | Zendy; KinHung Chow | Zendy; WH Seto | Zendy

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Emergence of Fluoroquinolone Resistance among Multiply Resistant Strains of Streptococcus pneumoniae in Hong Kong

Author(s) -

PakLeung Ho,

TakLun Que,

Dominic NgaiChong Tsang,

TakKeung Ng,

KinHung Chow,

WH Seto

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.5.1310

Subject(s) - streptococcus pneumoniae , microgram , trovafloxacin , microbiology and biotechnology , ciprofloxacin , levofloxacin , penicillin , streptococcaceae , minimum inhibitory concentration , antimicrobial , antibacterial agent , chemistry , biology , antibiotics , in vitro , biochemistry

The MICs of 17 antimicrobial agents for 181 Streptococcus pneumoniae strains were determined by the E-test. Overall, 69.1% were penicillin resistant (MIC > 0.06 microgram/ml). Resistance to ciprofloxacin (MIC > 2 microgram/ml), levofloxacin (MIC > 2 microgram/ml), or trovafloxacin (MIC > 1 microgram/ml) was found in 12.1, 5.5, or 2.2% of the strains, respectively. These high rates of resistance raise concerns for the future.

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