In Vitro Activities of Ketolides HRM 3647 and HRM 3004, Levofloxacin, and Other Quinolones and Macrolides against Neisseria spp. and Moraxella catarrhalis | Zendy

J. A. Sáez-Nieto | Zendy; Julio A. Vázquez | Zendy

Open Access

In Vitro Activities of Ketolides HRM 3647 and HRM 3004, Levofloxacin, and Other Quinolones and Macrolides against Neisseria spp. and Moraxella catarrhalis

Author(s) -

J. A. Sáez-Nieto,

Julio A. Vázquez

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.4.983

Subject(s) - microbiology and biotechnology , moraxella catarrhalis , neisseria , ketolide , levofloxacin , biology , moraxella , moraxella (branhamella) catarrhalis , neisseria gonorrhoeae , antibacterial agent , antibiotics , bacteria , haemophilus influenzae , genetics

In vitro activities of the ketolides HMR 3647 [corrected] and HMR 3004 [corrected] against pathogenic Neisseria gonorrhoeae and N. meningitidis, saprophytic Neisseria isolates, and Moraxella catarrhalis were determined. The comparison of ketolide activities with those of the other macrolides shows a much better activity in the majority of species, with macrolide MICs at which 90% of the isolates are inhibited between 8- and 10-fold higher.

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