In Vitro Susceptibilities of Mycoplasma hominis to Six Fluoroquinolones as Determined by E Test
Author(s) -
Ken B. Waites,
Kay C. Canupp,
George E. Kenny
Publication year - 1999
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.43.10.2571
Subject(s) - trovafloxacin , sparfloxacin , moxifloxacin , mycoplasma hominis , microbiology and biotechnology , agar dilution , ciprofloxacin , levofloxacin , agar dilution method , ofloxacin , antibacterial agent , mycoplasmataceae , gatifloxacin , lomefloxacin , minimum inhibitory concentration , biology , chemistry , mycoplasma , antibiotics , mollicutes
Twenty isolates of Mycoplasma hominis were tested for their susceptibility to six fluoroquinolones by the E test. The MICs at which 90% of the isolates were inhibited (in micrograms per milliliter) were as follows: sparfloxacin, 0.031; clinafloxacin, moxifloxacin, and trovafloxacin, 0.063; levofloxacin, 0.25; and ciprofloxacin, 0.5. Increasing the amount of inoculum or incubation in CO(2) elevated MICs by </=1 dilution. E tests produce fluoroquinolone MICs comparable to those obtained by agar and microbroth dilution for M. hominis.
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