Analysis of  grlA Mutations in Clinical Isolates of Staphylococcus aureus with Different Levels of Quinolone Resistance  | Zendy

J. A. Martínez | Zendy; G. Aparicio Ortiz | Zendy; Manuel Segovia | Zendy; M. A. Alonso | Zendy; Montero Gutiérrez | Zendy; Juan Luis Muñoz Bellido | Zendy; J.Á. García-Rodríguez | Zendy

Open Access

Analysis of grlA Mutations in Clinical Isolates of Staphylococcus aureus with Different Levels of Quinolone Resistance

Author(s) -

J. A. Martínez,

G. Aparicio Ortiz,

Manuel Segovia,

M. A. Alonso,

Montero Gutiérrez,

Juan Luis Muñoz Bellido,

J.Á. García-Rodríguez

Publication year - 1998

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.42.5.1306

Subject(s) - staphylococcus aureus , quinolone , microbiology and biotechnology , antibiotics , staphylococcus , bacteria , chemistry , biology , genetics

Some years ago the Staphylococcus aureus DNA topoiso-merase IV genes were cloned and named grlA and grlB ([2][1]). Alterations in the GrlA subunit have been associated with fluoroquinolone resistance in clinical isolates ([2][1]). Further work with laboratory mutants supported data which indicated

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research