Open AccessTetracycline Resistance in Salmonella enterica subsp. enterica Serovar Dublin
Author(s) -
Gabriele Frech,
Štefan Schwarz
Publication year - 1998
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.42.5.1288
Subject(s) - salmonella enterica , tetracycline , transposable element , plasmid , biology , microbiology and biotechnology , serotype , escherichia coli , salmonella , enterobacteriaceae , transposon mutagenesis , genetics , gene , virology , genome , bacteria , antibiotics
The 47-kbp plasmid pGFT1 from Salmonella enterica subsp. enterica serovar Dublin mediated tetracycline resistance via a tet(A) gene located on an integrated copy of a Tn1721-analogous transposon. The integration site of the transposon was located within the reading frame of a fip gene. Plasmid pGFT1 was shown to be conjugative and to be able to replicate and express tetracycline resistance in Escherichia coli.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom