Antimicrobial Resistance in Shigella flexneri and Shigella sonnei in Hong Kong, 1986 to 1995 | Zendy

Yiu-Wai Chu | Zendy; Elizabeth T. S. Houang | Zendy; Donald J. Lyon | Zendy; Julia Ling | Zendy; Tak-keung Ng | Zendy; Augustine F. Cheng | Zendy

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Antimicrobial Resistance in Shigella flexneri and Shigella sonnei in Hong Kong, 1986 to 1995

Author(s) -

Yiu-Wai Chu,

Elizabeth T. S. Houang,

Donald J. Lyon,

Julia Ling,

Tak-keung Ng,

Augustine F. Cheng

Publication year - 1998

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.42.2.440

Subject(s) - shigella flexneri , shigella sonnei , shigella , microbiology and biotechnology , nalidixic acid , antimicrobial , biology , shigellosis , antibiotic resistance , enterobacteriaceae , virology , antibiotics , bacteria , salmonella , escherichia coli , genetics , gene

Three hundred and thirty-three Shigella isolates obtained in 1986 to 1995 were tested for their susceptibilities to 19 antimicrobial agents. Nalidixic acid resistance had emerged in 59.6% of Shigella flexneri isolates during 1994 to 1995, with all tested resistant isolates having the mutation in gyrA encoding the Ser-83 alteration. Multiresistance (resistance to four or more agents) was more common in S. flexneri than in Shigella sonnei.

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