In Vitro Activity of a New Polyene, SPA-S-843, against Yeasts | Zendy

Claudio Rimaroli | Zendy; T. Bruzzese | Zendy

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In Vitro Activity of a New Polyene, SPA-S-843, against Yeasts

Author(s) -

Claudio Rimaroli,

T. Bruzzese

Publication year - 1998

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.42.11.3012

Subject(s) - candida krusei , candida tropicalis , candida glabrata , candida albicans , microbiology and biotechnology , polyene , amphotericin b , in vitro , fungi imperfecti , biology , nystatin , cryptococcus , antifungal , biochemistry

The in vitro activity of a new water-soluble polyene, SPA-S-843, was evaluated against 116 strains of Candida, Cryptococcus, and Saccharomyces spp. and compared with that of amphotericin B. SPA-S-843 demonstrated better inhibitory activity against all of the yeasts examined and better fungicidal activity against Candida albicans, Candida glabrata, Candida krusei, and Candida tropicalis than did amphotericin B.

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