In Vitro Susceptibility of Coxiella burnetii to Trovafloxacin in Comparison with Susceptibilities to Pefloxacin, Ciprofloxacin, Ofloxacin, Doxycycline, and Clarithromycin | Zendy

Achilleas Gikas | Zendy; Ioanna Spyridaki | Zendy; Anna Psaroulaki | Zendy; Diamantis Kofterithis | Zendy; Yannis Tselentis | Zendy

Open Access

In Vitro Susceptibility of Coxiella burnetii to Trovafloxacin in Comparison with Susceptibilities to Pefloxacin, Ciprofloxacin, Ofloxacin, Doxycycline, and Clarithromycin

Author(s) -

Achilleas Gikas,

Ioanna Spyridaki,

Anna Psaroulaki,

Diamantis Kofterithis,

Yannis Tselentis

Publication year - 1998

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.42.10.2747

Subject(s) - trovafloxacin , pefloxacin , ofloxacin , ciprofloxacin , microbiology and biotechnology , antibacterial agent , clarithromycin , doxycycline , antibiotics , chemistry , pharmacology , medicine , biology

The antibiotic susceptibilities of eight Greek isolates ofCoxiella burnetii to trovafloxacin were determined by the shell vial assay. MICs of trovafloxacin and ofloxacin ranged from 1 to 2 μg/ml, those of pefloxacin ranged from 1 to 4 μg/ml, those of ciprofloxacin ranged from 4 to 8 μg/ml, those of doxycycline ranged from 1 to 2 μg/ml, and those of clarithromycin ranged from 2 to 4 μg/ml. Trovafloxacin exhibited no activity againstC. burnetii at 4 μg/ml.

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