Therapeutic Effects of Water-Soluble Echinocandin Compounds on Pneumocystis Pneumonia in Mice | Zendy

Takahisa Furuta | Zendy; Hideyuki Muramatsu | Zendy; Akihiko Fujie | Zendy; Shiro Fujihira | Zendy; Noor Rain Abudullah | Zendy; Somei Kojima | Zendy

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Therapeutic Effects of Water-Soluble Echinocandin Compounds on Pneumocystis Pneumonia in Mice

Author(s) -

Takahisa Furuta,

Hideyuki Muramatsu,

Akihiko Fujie,

Shiro Fujihira,

Noor Rain Abudullah,

Somei Kojima

Publication year - 1998

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.42.1.37

Subject(s) - echinocandin , pneumonia , echinocandins , water soluble , pneumocystis pneumonia , microbiology and biotechnology , pharmacology , therapeutic effect , medicine , biology , chemistry , antifungal , caspofungin , amphotericin b , fluconazole , organic chemistry , pneumocystis jirovecii

The therapeutic effectiveness of water-soluble echinocandin compounds obtained from Coleophoma empetri F-11899, which has a strong inhibitory effect on the growth of fungi, was examined in nude mice with experimental Pneumocystis pneumonia. The studies demonstrated the potential usefulness of the compounds.

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