Active efflux of antimicrobial agents in wild-type strains of enterococci | Zendy

Christy Lynch | Zendy; Patrice Courvalin | Zendy; Hiroshi Nikaido | Zendy

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Active efflux of antimicrobial agents in wild-type strains of enterococci

Author(s) -

Christy Lynch,

Patrice Courvalin,

Hiroshi Nikaido

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.4.869

Subject(s) - efflux , enterococcus faecalis , tetracycline , microbiology and biotechnology , antimicrobial , norfloxacin , enterococcus , chloramphenicol , enterococcus faecium , biology , antibacterial agent , antibiotics , bacteria , ciprofloxacin , staphylococcus aureus , biochemistry , genetics

Enterococci are intrinsically resistant to numerous antimicrobial agents. We examined the energy-dependent efflux of radiolabeled drugs from four reference strains of Enterococcus faecalis and a strain of Enterococcus faecium and found that most strains pumped out norfloxacin and chloramphenicol. Efflux of tetracycline was detected only in certain strains.

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