In vitro activities of new quinolones against Helicobacter pylori | Zendy

Maria Luigia Carbone | Zendy; M T Fera | Zendy; Violetta Cecchetti | Zendy; Oriana Tabarrini | Zendy; E. Losi | Zendy; V Cusumano | Zendy; Giuseppe Teti | Zendy

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In vitro activities of new quinolones against Helicobacter pylori

Author(s) -

Maria Luigia Carbone,

M T Fera,

Violetta Cecchetti,

Oriana Tabarrini,

E. Losi,

V Cusumano,

Giuseppe Teti

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.12.2790

Subject(s) - helicobacter pylori , in vitro , microbiology and biotechnology , antibacterial agent , minimum inhibitory concentration , biology , antibiotics , chemistry , biochemistry , genetics

Compounds belonging to a new class of quinolones in which the fundamental C-6 fluorine atom was replaced were evaluated for in vitro antibacterial activity against 32 Helicobacter pylori strains. Since these substitutions resulted in higher inhibitory activities, these new desfluoroquinolones may be useful in eradicating H. pylori infections.

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