Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections | Zendy

Pascal Ringwald | Zendy; Jean Bickii | Zendy; A SaméEkobo | Zendy; Léonardo K. Basco | Zendy

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Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections

Author(s) -

Pascal Ringwald,

Jean Bickii,

A SaméEkobo,

Léonardo K. Basco

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.10.2317

Subject(s) - plasmodium ovale , plasmodium malariae , chloroquine , malaria , plasmodium (life cycle) , virology , medicine , plasmodium falciparum , pharmacology , biology , immunology , parasite hosting , plasmodium vivax , world wide web , computer science

The clinical efficacy of oral pyronaridine was assessed in 22 symptomatic Cameroonian patients infected with Plasmodium ovale or Plasmodium malariae. All patients were cured on or before day 4. In vitro drug assays confirmed the sensitivity of P. ovale and P. malariae isolates to chloroquine and pyronaridine.

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