In vitro activities in new oxazolidinone antimicrobial agents against enterococci
Author(s) -
George M. Eliopoulos,
Christine Wennersten,
Howard S. Gold,
Robert C. Moellering
Publication year - 1996
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.40.7.1745
Subject(s) - antimicrobial , agar dilution , minocycline , ampicillin , agar dilution method , microbiology and biotechnology , in vitro , agar , enterococcus , antibacterial agent , vancomycin , biology , antibiotics , chemistry , bacteria , minimum inhibitory concentration , staphylococcus aureus , biochemistry , genetics
The comparative in vitro activities of two new oxazolidinone antimicrobial agents, U-100592 and U-100766, against 180 isolates of enterococci representing several resistance profiles were examined by using an agar dilution technique. The two oxazolidinones inhibited all isolates, including strains resistant to vancomycin, ampicillin, and minocycline, at concentrations between 1 and 4 micrograms/ml.
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