Unique susceptibility of Helicobacter pylori to simethicone emulsifiers in alimentary therapeutic agents | Zendy

Anne Kane | Zendy; Andrew G. Plaut | Zendy

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Unique susceptibility of Helicobacter pylori to simethicone emulsifiers in alimentary therapeutic agents

Author(s) -

Anne Kane,

Andrew G. Plaut

Publication year - 1996

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.40.2.500

Subject(s) - helicobacter pylori , bacteria , in vitro , microbiology and biotechnology , spirillaceae , antibiotics , helicobacter , antibacterial agent , pharmacology , chemistry , biology , gastroenterology , biochemistry , medicine , gastritis , genetics

Helicobacter pylori is killed in vitro by polyoxyethylene acyl esters and ethers similar to simethicone emulsifiers in therapeutic antifoams. The MBC of these compounds for Helicobacter pylori was less than 20 micrograms/ml, while other gram-negative bacteria were unaffected by much higher concentrations of up to 50 mg/ml.

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