Biosynthesis of Monensin | Zendy

L. E. Day | Zendy; James W. Chamberlin | Zendy; E. Z. Gordee | Zendy; S. Chen | Zendy; Marvin Gorman | Zendy; Robert L. Hamill | Zendy; Terence M. Ness | Zendy; R. E. Weeks | Zendy; Ronald M. Stroshane | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Biosynthesis of Monensin

Author(s) -

L. E. Day,

James W. Chamberlin,

E. Z. Gordee,

S. Chen,

Marvin Gorman,

Robert L. Hamill,

Terence M. Ness,

R. E. Weeks,

Ronald M. Stroshane

Publication year - 1973

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.4.4.410

Subject(s) - monensin , propionate , biosynthesis , butyrate , methionine , hydroxymethyl , chemistry , biochemistry , stereochemistry , fermentation , enzyme , amino acid

The biosynthesis of monensin byStreptomyces cinnamonensis was studied by using14 C-labeled glucose, acetate, propionate, butyrate, and methionine. The results indicated that the antibiotic is synthesized from five acetate, seven propionate, and one butyrate molecules. Theo -methyl group of monensin is derived from methionine, whereas the terminal hydroxymethyl group is incorporated from acetate.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research