Open AccessDetermination of antimicrobial susceptibilities of Canadian isolates of Haemophilus influenzae and characterization of their beta-lactamases. Canadian Haemophilus Study Group
Author(s) -
S. R. Scriver,
Sharon Walmsley,
C. L. Kau,
Daryl J. Hoban,
James Brunton,
Allison McGeer,
T C Moore,
Evelyn Witwicki
Publication year - 1994
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.38.7.1678
Subject(s) - haemophilus influenzae , microbiology and biotechnology , ampicillin , haemophilus , beta lactamase , antimicrobial , beta (programming language) , amp resistance , biology , antibiotics , bacteria , escherichia coli , gene , genetics , computer science , programming language
Susceptibility testing of 1,688 Haemophilus influenzae isolates found 484 ampicillin-resistant strains; 474 strains (28.4%) were beta-lactamase positive, and 5 strains (0.4%) were non-beta-lactamase producers. Restriction enzyme digestion of the beta-lactamase amplicon determined that, of 157 strains, 11 (7.0%) contained ROB-1 beta-lactamase and 146 (93.0%) contained a TEM-type beta-lactamase.