Open AccessIn vitro activities of enoxacin, enrofloxacin, sparfloxacin, and ciprofloxacin against Escherichia coli strains isolated from diarrheic lambs and kids
Author(s) -
María Dolores Cid Vázquez,
Segundo Píriz,
José A. Ruiz-Santa-Quiteria,
Javier Valle,
Sergio Javier Martínez García,
S. Vadillo,
Ricardo de la Fuente
Publication year - 1994
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.38.10.2469
Subject(s) - sparfloxacin , enrofloxacin , ciprofloxacin , enoxacin , microbiology and biotechnology , escherichia coli , biology , pefloxacin , antibacterial agent , bacteria , ofloxacin , antibiotics , biochemistry , genetics , gene
The in vitro activities of four fluoroquinolone compounds were tested against 92 Escherichia coli strains of ovine and caprine origin under aerobic and anaerobic incubation conditions. The four fluoroquinolones proved to be highly effective against the E. coli isolates tested. When bacteria were cultured anaerobically, at least fourfold increases in the MICs of enoxacin for the strains occurred and no detectable changes in enrofloxacin, sparfloxacin, and ciprofloxacin MICs occurred.
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