Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens | Zendy

James R. Johnson | Zendy; Terriel Berggren | Zendy; Ann J. Conway | Zendy

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Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens

Author(s) -

James R. Johnson,

Terriel Berggren,

Ann J. Conway

Publication year - 1993

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.37.9.2033

Subject(s) - nitrofurazone , nitrofurantoin , urinary system , catheter , microbiology and biotechnology , medicine , pseudomonas aeruginosa , antibacterial agent , surgery , chemistry , biology , bacteria , antibiotics , ciprofloxacin , traditional medicine , genetics

Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by < or = 64 micrograms of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r2 = 0.93, P = 0.0001).

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