Effects of subinhibitory concentrations of vancomycin and teicoplanin on adherence of staphylococci to tissue culture plates | Zendy

H. Carsenti-Etesse | Zendy; J. Durant | Zendy; José M. Entenza | Zendy; V. Mondain | Zendy; C. Pradier | Zendy; E. Bernard | Zendy; P. Dellamonica | Zendy

Open Access

Effects of subinhibitory concentrations of vancomycin and teicoplanin on adherence of staphylococci to tissue culture plates

Author(s) -

H. Carsenti-Etesse,

J. Durant,

José M. Entenza,

V. Mondain,

C. Pradier,

E. Bernard,

P. Dellamonica

Publication year - 1993

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.37.4.921

Subject(s) - teicoplanin , vancomycin , staphylococcus epidermidis , staphylococcus aureus , microbiology and biotechnology , micrococcaceae , staphylococcal infections , biology , antibiotics , antibacterial agent , bacteria , medicine , genetics

Bacterial adhesion is the first step in infection of medical devices. Staphylococcus aureus and Staphylococcus epidermidis are the pathogens recovered most often. The effects of subinhibitory concentrations of vancomycin and teicoplanin on the adherence of eight clinical strains of S. aureus and eight strains of S. epidermidis to tissue culture plates in vitro were tested. The mean relative inhibitions of adherence at one-fourth and one-eighth the MIC were statistically different for teicoplanin and vancomycin. Slime production seemed not to be involved in adherence.

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