Open AccessSequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes
Author(s) -
Louis B. Rice,
Steve H. Marshall,
Lenore L. Carias,
Lorraine Sutton,
George A. Jacoby
Publication year - 1993
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.37.12.2760
Subject(s) - sequence (biology) , gene , biology , beta (programming language) , genetics , computational biology , computer science , programming language
Genes for MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamases have been cloned and sequenced. The gene for MGH-1 has the sequence of blaTEM-10, YOU-2 has that of blaTEM-12, and YOU-1 has that of blaTEM-26. All have evolved from blaTEM-1b but have the strong dual promoter sequence of blaTEM-2.