In vitro activities of streptomycin and 11 oral antimicrobial agents against clinical isolates of Klebsiella rhinoscleromatis | Zendy

Bradley A. Perkins | Zendy; Richard J. Hamill | Zendy; Daniel M. Musher | Zendy; C M O'Hara | Zendy

Open Access

In vitro activities of streptomycin and 11 oral antimicrobial agents against clinical isolates of Klebsiella rhinoscleromatis

Author(s) -

Bradley A. Perkins,

Richard J. Hamill,

Daniel M. Musher,

C M O'Hara

Publication year - 1992

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.36.8.1785

Subject(s) - microbiology and biotechnology , streptomycin , ciprofloxacin , trimethoprim , tetracycline , antimicrobial , antibiotics , sulfamethoxazole , chloramphenicol , biology , amoxicillin , klebsiella , cefuroxime , cefpodoxime , antibacterial agent , escherichia coli , biochemistry , gene

We tested in vitro the activities of streptomycin and tetracycline--antibiotics that have long been used to treat rhinoscleroma--as well as several newer oral agents by using 23 isolates of the causative organism Klebsiella rhinoscleromatis. All isolates were inhibited by clinically achievable concentrations of trimethoprim-sulfamethoxazole, amoxicillin-clavulanate, chloramphenicol, ciprofloxacin, cephalexin, cefuroxime, and cefpodoxime.

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