A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone | Zendy

Agnes Marie Sá Figueiredo | Zendy; James D. Connor | Zendy; A Severin | Zendy; M. V. Vaz Pato | Zendy; Alexander Tomasz | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone

Author(s) -

Agnes Marie Sá Figueiredo,

James D. Connor,

A Severin,

M. V. Vaz Pato,

Alexander Tomasz

Publication year - 1992

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.36.4.886

Subject(s) - cefotaxime , ceftriaxone , streptococcus pneumoniae , benzylpenicillin , microbiology and biotechnology , penicillin , meningitis , pneumococcal infections , cephalosporin , serotype , antibiotics , streptococcaceae , medicine , penicillin binding proteins , antibacterial agent , biology , surgery

A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5 micrograms/ml each) are higher than that of benzylpenicillin (0.3 micrograms/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research