Protection of Pseudomonas aeruginosa against ciprofloxacin and beta-lactams by homologous alginate | Zendy

Norman Hodges | Zendy; C A Gordon | Zendy

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Protection of Pseudomonas aeruginosa against ciprofloxacin and beta-lactams by homologous alginate

Author(s) -

Norman Hodges,

C A Gordon

Publication year - 1991

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.35.11.2450

Subject(s) - ticarcillin , pseudomonas aeruginosa , ciprofloxacin , microbiology and biotechnology , ceftazidime , biofilm , gentamicin , chemistry , pseudomonadales , aminoglycoside , pseudomonas , biology , antibiotics , bacteria , genetics

Pseudomonas aeruginosa-derived alginate but no other neutral and negatively charged polysaccharides protected mucoid and nonmucoid strains of that organism against ciprofloxacin, gentamicin, ticarcillin, and ceftazidime. Data indicate that alginate has an intrinsic protective effect which is independent of diffusion, charge, or biofilm phenomena.

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